CYB210010

CYB210010
臨床資料
其他名稱	2C-T-FM; 2C-T-36; CYB-210010; CYB-2108; CYB2108; 2,5-Dimethoxy-4-(trifluoromethyl-sulfanyl)phenethylamine
藥物類別	Serotonin 5-HT2 receptor agonist; Serotonergic psychedelic; Hallucinogen
識別資訊
	IUPAC命名法 2-[2,5-dimethoxy-4-(trifluoromethylsulfanyl)phenyl]ethanamine; ;
CAS號	2762567-99-5
PubChem CID	168072159;
化學資訊
化學式	C11H14F3NO2S
摩爾質量	281.29 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES COC1=CC(=C(C=C1CCN)OC)SC(F)(F)F;
	InChI InChI=1S/C11H14F3NO2S/c1-16-8-6-10(18-11(12,13)14)9(17-2)5-7(8)3-4-15/h5-6H,3-4,15H2,1-2H3; Key:VOGDBAZLGHXJBS-UHFFFAOYSA-N;

CYB210010（也稱為2C-T-TFM、2C-T-36，化學名：4-三氟甲硫基-2,5-二甲氧基苯乙胺，英語：2,5-dimethoxy-4-(trifluoromethylsulfanyl)phenethylamine）是一種含氮有機化合物，化學式為C₁₁H₁₄F₃NO₂S，屬於含硫2,5-二甲氧基苯乙胺衍生物（2C類化合物），能作為致幻劑^[2]，2023年由Cybin公司的研發人員首次合成^[3]。

參考文獻

^ 2-[2,5-Dimethoxy-4-(trifluoromethylsulfanyl)phenyl]ethanamine. PubChem. [10 November 2024].
^ WO 2023156450,Nivorozhkin A, JA Hartsel, Canal CE, Salituro FG, Mueller TA, Greene BJ, Belser A, Avery KL, Reichelt AC, Varty GB, Palfreyman M,「Therapeutic phenethylamine compositions and methods of use」,發表於24 August 2023
^ Palfreyman M, Varty G, Canal C, Hartsel J, Tyagi R, Avery K, Morgan M, Mueller T, Reichelt A, Pathare P, Stang E, Nivorozhkin A. ACNP 62nd Annual Meeting: Poster Abstracts P251 – P500: P405. Discovery and Preclinical Characterization of the Phenylalkylamine, CYB210010, a Potent and Long-Acting Serotonin 5-HT2A Receptor Agonist. Neuropsychopharmacology. December 2023, 48 (Suppl 1): 211–354 (299–299. PMC 10729596 . PMID 38040810. doi:10.1038/s41386-023-01756-4.

外部連結

[PubChem-1] 2-[2,5-Dimethoxy-4-(trifluoromethylsulfanyl)phenyl]ethanamine. PubChem. [10 November 2024].

[WO2023156450A1-2] WO 2023156450,Nivorozhkin A, JA Hartsel, Canal CE, Salituro FG, Mueller TA, Greene BJ, Belser A, Avery KL, Reichelt AC, Varty GB, Palfreyman M,「Therapeutic phenethylamine compositions and methods of use」,發表於24 August 2023

[PalfreymanVartyCanal2023-3] Palfreyman M, Varty G, Canal C, Hartsel J, Tyagi R, Avery K, Morgan M, Mueller T, Reichelt A, Pathare P, Stang E, Nivorozhkin A. ACNP 62nd Annual Meeting: Poster Abstracts P251 – P500: P405. Discovery and Preclinical Characterization of the Phenylalkylamine, CYB210010, a Potent and Long-Acting Serotonin 5-HT2A Receptor Agonist. Neuropsychopharmacology. December 2023, 48 (Suppl 1): 211–354 (299–299. PMC 10729596 . PMID 38040810. doi:10.1038/s41386-023-01756-4.

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