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普羅雌烯

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普羅雌烯
臨床資料
商品名英語Drug nomenclatureColpotrofin, Colpotrophine, Delipoderm
其他名稱Estradiol 3-propyl 17β-methyl diether; 17β-Methoxy-3-propoxyestra-1,3,5(10)-triene
給藥途徑外用藥物
藥物類別雌激素雌激素醚
ATC碼
識別資訊
  • (8R,9S,13S,14S)-17-methoxy-13-methyl-3-propoxy-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene
CAS號39219-28-8
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.049.401 編輯維基數據鏈接
化學資訊
化學式C22H32O2
摩爾質量328.50 g·mol−1
3D模型(JSmol英語JSmol
  • CCCOc1ccc2c(c1)CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4OC)C
  • InChI=1S/C22H32O2/c1-4-13-24-16-6-8-17-15(14-16)5-7-19-18(17)11-12-22(2)20(19)9-10-21(22)23-3/h6,8,14,18-21H,4-5,7,9-13H2,1-3H3/t18-,19-,20+,21?,22+/m1/s1 ☒N
  • Key:IUWKNLFTJBHTSD-QIKJAYGVSA-N ☒N

普羅雌烯INNPromestriene,化學名:雌二醇-3-丙基-17β-甲基二醚,estradiol 3-propyl 17β-methyl diether,商品名有Colpotrofin、Colpotrophine、Delipoderm等)是一種有機化合物,化學式C
22
H
32
O
2
,屬於一種雌激素,以外用乳霜治療婦女的萎縮性陰道炎[1][2][3][4][5]

參考文獻

[編輯]
  1. ^ Del Pup L, Di Francia R, Cavaliere C, Facchini G, Giorda G, De Paoli P, Berretta M. Promestriene, a specific topic estrogen. Review of 40 years of vaginal atrophy treatment: is it safe even in cancer patients?. Anti-Cancer Drugs. November 2013, 24 (10): 989–998. PMID 24080714. S2CID 3458356. doi:10.1097/CAD.0b013e328365288e. 
  2. ^ Ganellin CR, Triggle DJ. Dictionary of Pharmacological Agents. CRC Press. 21 November 1996: 1671–. ISBN 978-0-412-46630-4. 
  3. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000: 1248, 1266, 1318, 1557. ISBN 978-3-88763-075-1. 
  4. ^ William Andrew Publishing. Pharmaceutical Manufacturing Encyclopedia, 3rd Edition. Elsevier. 22 October 2013: 270–271. ISBN 978-0-8155-1856-3. 
  5. ^ Muller. European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. 19 June 1998: 289, 33 2. ISBN 978-3-7692-2114-5.