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O-823

維基百科,自由的百科全書
O-823
識別資訊
  • 7-[(6aR,10aR)-1-hydroxy-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-3-yl]hept-5-ynenitrile
CAS號184433-64-5  checkY
PubChem CID
ChemSpider
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C23H27NO2
摩爾質量349.47 g·mol−1
3D模型(JSmol英語JSmol
  • Oc2cc(CC#CCCCC#N)cc(OC1(C)C)c2C3C1CC=C(C)C3
  • InChI=1S/C23H27NO2/c1-16-10-11-19-18(13-16)22-20(25)14-17(9-7-5-4-6-8-12-24)15-21(22)26-23(19,2)3/h10,14-15,18-19,25H,4,6,8-9,11,13H2,1-3H3/t18-,19-/m1/s1 checkY
  • Key:MZMMIGOIGWVGEH-RTBURBONSA-N checkY

O-823是一種含氮有機化合物,化學式C
26
H
39
NO
3
,屬於一種大麻素,由美國Organix Inc公司開發,是大麻素受體CB1部分激動劑[1][2][3]

參考文獻

[編輯]
  1. ^ Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. European Journal of Pharmacology. November 1996, 315 (2): 195–201. PMID 8960884. doi:10.1016/s0014-2999(96)00631-0. 
  2. ^ Griffin G, Wray EJ, Rorrer WK, Crocker PJ, Ryan WJ, Saha B, et al. An investigation into the structural determinants of cannabinoid receptor ligand efficacy. British Journal of Pharmacology. April 1999, 126 (7): 1575–84. PMC 1565939可免費查閱. PMID 10323589. doi:10.1038/sj.bjp.0702469. 
  3. ^ Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. October 1999, 128 (3): 684–8. PMC 1571656可免費查閱. PMID 10516649. doi:10.1038/sj.bjp.0702806.