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环丙洛尔

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环丙洛尔
临床资料
其他名称Cycloprolol; SL-75177
识别信息
  • 1-[4-[2-(cyclopropylmethoxy)ethoxy]phenoxy]-3-(propan-2-ylamino)propan-2-ol
CAS号63659-12-1  checkY
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H29NO4
摩尔质量323.43 g·mol−1
3D模型(JSmol英语JSmol
  • CC(C)NCC(COC1=CC=C(C=C1)OCCOCC2CC2)O
  • InChI=1S/C18H29NO4/c1-14(2)19-11-16(20)13-23-18-7-5-17(6-8-18)22-10-9-21-12-15-3-4-15/h5-8,14-16,19-20H,3-4,9-13H2,1-2H3
  • Key:JNDJPKHYZWRRIS-UHFFFAOYSA-N

环丙洛尔(英语:Cicloprolol,研发代号:SL-75177)是一种含氮有机化合物,化学式C
18
H
29
NO
4
,能作为β受体阻滞剂抗高血压药[1][2][3][4][5]

参考文献

[编辑]
  1. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014: 272 [29 August 2024]. ISBN 978-1-4757-2085-3. 
  2. ^ Morton IK, Hall JM. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. 2012: 88 [2024-08-29]. ISBN 978-94-011-4439-1. 
  3. ^ Persson H, Erhardt L. Beta receptor antagonists in the treatment of heart failure. Cardiovascular Drugs and Therapy. June 1991, 5 (3): 589–604. PMID 1678962. doi:10.1007/BF03029728. 
  4. ^ Waller DG. Beta-adrenoceptor partial agonists: a renaissance in cardiovascular therapy?. British Journal of Clinical Pharmacology. August 1990, 30 (2): 157–171. PMC 1368213可免费查阅. PMID 1976342. doi:10.1111/j.1365-2125.1990.tb03760.x. 
  5. ^ Cocco G, Alfiero R, Pouleur H. An evaluation of the safety of the beta-modulator cicloprolol in chronic heart failure. Clinical Cardiology. January 1992, 15 (1): 38–42. PMID 1347258. doi:10.1002/clc.4960150109可免费查阅.